6BR6

N2 neuraminidase in complex with a novel antiviral compound

6BR6 の概要

• エントリーDOI: 10.2210/pdb6br6/pdb
• 関連するPDBエントリー: 6BR5
• 分子名称: Neuraminidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: complex, hydrolase
• 由来する生物種: Influenza A virus (A/Perth/16/2009(H3N2))
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44607.19

構造登録者

Li, L.H.,Ve, T.,Pascolutti, M.,Hadhazi, A.,Bailly, B.,Thomson, R.J.,Gao, G.F.,von Itzstein, M. (登録日: 2017-11-30, 公開日: 2018-03-07, 最終更新日: 2020-07-29)

• 主引用文献: Hadhazi, A.,Li, L.,Bailly, B.,Maggioni, A.,Martin, G.,Dirr, L.,Dyason, J.C.,Thomson, R.J.,Gao, G.F.,Borbas, A.,Ve, T.,Pascolutti, M.,von Itzstein, M.; A Sulfonozanamivir Analogue Has Potent Anti-influenza Virus Activity.; ChemMedChem, 13:785-789, 2018; PubMed: 29453852; DOI: 10.1002/cmdc.201800092

実験手法

X-RAY DIFFRACTION (2.03983884352 Å)