6BQB
MGG4 Fab in complex with peptide
Summary for 6BQB
Entry DOI | 10.2210/pdb6bqb/pdb |
Descriptor | MGG4 Fab light chain, MGG4 Fab heavy chain, N-terminal junction peptide, ... (5 entities in total) |
Functional Keywords | human fab fragment peptide binding plasmodium falciparum circumsporozoite protein, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 49943.60 |
Authors | Oyen, D.,Tan, J.,Lanzavecchia, A.,Wilson, I.A. (deposition date: 2017-11-27, release date: 2018-03-07, Last modification date: 2018-04-25) |
Primary citation | Tan, J.,Sack, B.K.,Oyen, D.,Zenklusen, I.,Piccoli, L.,Barbieri, S.,Foglierini, M.,Fregni, C.S.,Marcandalli, J.,Jongo, S.,Abdulla, S.,Perez, L.,Corradin, G.,Varani, L.,Sallusto, F.,Sim, B.K.L.,Hoffman, S.L.,Kappe, S.H.I.,Daubenberger, C.,Wilson, I.A.,Lanzavecchia, A. A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nat. Med., 24:401-407, 2018 Cited by PubMed: 29554084DOI: 10.1038/nm.4513 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.769 Å) |
Structure validation
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