6BPU

Crystal structure of ferrous form of the F2-Tyr157 human cysteine dioxygenase with both uncrosslinked and crosslinked cofactor

Summary for 6BPU

Entry DOI	10.2210/pdb6bpu/pdb
Descriptor	Cysteine dioxygenase type 1, FE (II) ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	cysteine, cys-tyr cofactor, iron, unnatural amino acid, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	23694.15
Authors	Liu, A.,Li, J.,Shin, I. (deposition date: 2017-11-26, release date: 2018-07-04, Last modification date: 2023-11-15)
Primary citation	Li, J.,Griffith, W.P.,Davis, I.,Shin, I.,Wang, J.,Li, F.,Wang, Y.,Wherritt, D.J.,Liu, A. Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat. Chem. Biol., 14:853-860, 2018 Cited by PubMed: 29942080 DOI: 10.1038/s41589-018-0085-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation