6BM0

Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution

Summary for 6BM0

Entry DOI	10.2210/pdb6bm0/pdb
EMDB information	7112 7113 7114
Descriptor	Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33 (2 entities in total)
Functional Keywords	polyadenylation, scaffolding protein, wd40, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	228621.05
Authors	Sun, Y.,Zhang, Y.,Hamilton, K.,Walz, T.,Tong, L. (deposition date: 2017-11-12, release date: 2017-11-22, Last modification date: 2024-03-13)
Primary citation	Sun, Y.,Zhang, Y.,Hamilton, K.,Manley, J.L.,Shi, Y.,Walz, T.,Tong, L. Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proc. Natl. Acad. Sci. U.S.A., 115:E1419-E1428, 2018 Cited by PubMed: 29208711 DOI: 10.1073/pnas.1718723115 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation