6BJK

Human ABO(H) blood group glycosyltransferase GTB D302C mutant

Summary for 6BJK

Entry DOI	10.2210/pdb6bjk/pdb
Descriptor	ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), GLYCEROL (3 entities in total)
Functional Keywords	blood group transferases, glycosyltransferases, enzymes, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	34365.71
Authors	Gagnon, S.M.L.,Legg, M.S.G.,Evans, S.V. (deposition date: 2017-11-06, release date: 2018-09-19, Last modification date: 2023-10-04)
Primary citation	Gagnon, S.M.L.,Legg, M.S.G.,Polakowski, R.,Letts, J.A.,Persson, M.,Lin, S.,Zheng, R.B.,Rempel, B.,Schuman, B.,Haji-Ghassemi, O.,Borisova, S.N.,Palcic, M.M.,Evans, S.V. Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases. Glycobiology, 28:624-636, 2018 Cited by PubMed: 29873711 DOI: 10.1093/glycob/cwy051 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.12 Å)

Structure validation