6BGI

Cryo-EM structure of the TMEM16A calcium-activated chloride channel in nanodisc

Summary for 6BGI

• Entry DOI: 10.2210/pdb6bgi/pdb
• Related: 6BGJ
• EMDB information: 7095 7096
• Descriptor: Anoctamin-1, CALCIUM ION (2 entities in total)
• Functional Keywords: chloride channel, tmem16 family, membrane protein
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 211368.28

Authors

Dang, S.,Feng, S.,Tien, J.,Peters, C.J.,Bulkley, D.,Lolicato, M.,Zhao, J.,Zuberbuhler, K.,Ye, W.,Qi, J.,Chen, T.,Craik, C.S.,Jan, Y.N.,Minor Jr., D.L.,Cheng, Y.,Jan, L.Y. (deposition date: 2017-10-28, release date: 2017-12-27, Last modification date: 2024-03-13)

• Primary citation: Dang, S.,Feng, S.,Tien, J.,Peters, C.J.,Bulkley, D.,Lolicato, M.,Zhao, J.,Zuberbuhler, K.,Ye, W.,Qi, L.,Chen, T.,Craik, C.S.,Nung Jan, Y.,Minor, D.L.,Cheng, Y.,Yeh Jan, L.; Cryo-EM structures of the TMEM16A calcium-activated chloride channel.; Nature, 552:426-429, 2017; PubMed: 29236684; DOI: 10.1038/nature25024

Experimental method

ELECTRON MICROSCOPY (3.8 Å)