6BGB

Crystal Structure of the 16mer GCAGNCUUAAGUCUGC containing BrPh 7-triazolyl-8-aza-7-deazaadenosine

Summary for 6BGB

• Entry DOI: 10.2210/pdb6bgb/pdb
• Related: 4NFO 4NFP 4NFQ
• Descriptor: (5'-R(*GP*CP*AP*GP*(A7C)P*CP*UP*UP*AP*AP*GP*UP*CP*UP*GP*C)-3') (2 entities in total)
• Functional Keywords: duplex, structural classification, synthetic, rna
• Biological source: synthetic construct
• Total number of polymer chains: 3
• Total formula weight: 15966.41

Authors

Fisher, A.J.,Beal, P.A.,Mumbleau, M.M. (deposition date: 2017-10-27, release date: 2017-12-06, Last modification date: 2024-03-13)

• Primary citation: Suter, S.R.,Ball-Jones, A.,Mumbleau, M.M.,Valenzuela, R.,Ibarra-Soza, J.,Owens, H.,Fisher, A.J.,Beal, P.A.; Controlling miRNA-like off-target effects of an siRNA with nucleobase modifications.; Org. Biomol. Chem., 15:10029-10036, 2017; PubMed: 29164215; DOI: 10.1039/c7ob02654d

Experimental method

X-RAY DIFFRACTION (1.65 Å)