6BFL

Caspase-3 Mutant- D9A,D28A,T245D

Summary for 6BFL

• Entry DOI: 10.2210/pdb6bfl/pdb
• Related PRD ID: PRD_000238
• Descriptor: Caspase-3, AC-ASP-GLU-VAL-ASP-CMK, AZIDE ION, ... (5 entities in total)
• Functional Keywords: allosteric regulation; apoptosis; biophysics; caspase; computational biology; x-ray crystallography; fluorescence; molecular dynamics; protein evolution, apoptosis, apoptosis-inhibitor complex, apoptosis/inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: P42574 P42574
• Total number of polymer chains: 3
• Total formula weight: 32172.88

Authors

Thomas, M.E.,Grinshpon, R.,Swartz, P.D.,Clark, A.C. (deposition date: 2017-10-26, release date: 2018-02-21, Last modification date: 2018-04-25)

• Primary citation: Thomas, M.E.,Grinshpon, R.,Swartz, P.,Clark, A.C.; Modifications to a common phosphorylation network provide individualized control in caspases.; J. Biol. Chem., 293:5447-5461, 2018; PubMed: 29414778; DOI: 10.1074/jbc.RA117.000728

Experimental method

X-RAY DIFFRACTION (1.87 Å)