6BFB

Crystal structure of a F. nucleatum FMN riboswitch bound to WG-3

6BFB の概要

• エントリーDOI: 10.2210/pdb6bfb/pdb
• 分子名称: RNA (54-MER), RNA (56-MER), 5-[(3S,4S)-3-(dimethylamino)-4-hydroxypyrrolidin-1-yl]-6-fluoro-4-methyl-8-oxo-3,4-dihydro-8H-1-thia-4,9b-diazacyclopenta[cd]phenalene-9-carboxylic acid, ... (5 entities in total)
• 機能のキーワード: rna, translation, rna-inhibitor complex
• 由来する生物種: Fusobacterium nucleatum; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36004.93

構造登録者

Rizvi, N.F.,Fischmann, T.O. (登録日: 2017-10-26, 公開日: 2018-02-21, 最終更新日: 2024-03-06)

• 主引用文献: Rizvi, N.F.,Howe, J.A.,Nahvi, A.,Klein, D.J.,Fischmann, T.O.,Kim, H.Y.,McCoy, M.A.,Walker, S.S.,Hruza, A.,Richards, M.P.,Chamberlin, C.,Saradjian, P.,Butko, M.T.,Mercado, G.,Burchard, J.,Strickland, C.,Dandliker, P.J.,Smith, G.F.,Nickbarg, E.B.; Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.; ACS Chem. Biol., 13:820-831, 2018; PubMed: 29412640; DOI: 10.1021/acschembio.7b01013

実験手法

X-RAY DIFFRACTION (2.82 Å)