6BCK

Crystal Structure of Broadly Neutralizing Antibody N49P7 in Complex with HIV-1 Clade AE strain 93TH057 gp120 core.

Summary for 6BCK

Entry DOI	10.2210/pdb6bck/pdb
Descriptor	clade A/E 93TH057 HIV-1 gp120 core, N49P7 Fab heavy chain of N29P7 IgG, N49P7 Fab light chain from N49P7 IgG, ... (6 entities in total)
Functional Keywords	hiv-1, vrc01-class antibody, cd4 binding site, clade a/e 93th057 gp120, viral protein-immune system complex, n49p7, immune system, viral protein/immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	3
Total formula weight	88350.98
Authors	Tolbert, W.D.,Gohain, N.,Pazgier, M. (deposition date: 2017-10-20, release date: 2018-05-23, Last modification date: 2023-10-04)
Primary citation	Sajadi, M.M.,Dashti, A.,Rikhtegaran Tehrani, Z.,Tolbert, W.D.,Seaman, M.S.,Ouyang, X.,Gohain, N.,Pazgier, M.,Kim, D.,Cavet, G.,Yared, J.,Redfield, R.R.,Lewis, G.K.,DeVico, A.L. Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses. Cell, 173:1783-1795.e14, 2018 Cited by PubMed: 29731169 DOI: 10.1016/j.cell.2018.03.061 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation