6BBD

Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol

6BBD の概要

• エントリーDOI: 10.2210/pdb6bbd/pdb
• 関連するPDBエントリー: 4DN8
• 分子名称: Pulmonary surfactant-associated protein D, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: innate immunity, surfactant, n-linked glycan, c-type lectin, surfactant protein
• 由来する生物種: Sus scrofa (Pig)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17997.89

構造登録者

van Eijk, M.,Rynkiewicz, M.J.,Khatri, K.,Leymarie, N.,Zaia, J.,White, M.R.,Hartshorn, K.L.,Cafarella, T.R.,van Die, I.,Hessing, M.,Seaton, B.A.,Haagsman, H.P. (登録日: 2017-10-18, 公開日: 2018-05-23, 最終更新日: 2023-10-04)

• 主引用文献: van Eijk, M.,Rynkiewicz, M.J.,Khatri, K.,Leymarie, N.,Zaia, J.,White, M.R.,Hartshorn, K.L.,Cafarella, T.R.,van Die, I.,Hessing, M.,Seaton, B.A.,Haagsman, H.P.; Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus.; J. Biol. Chem., 293:10646-10662, 2018; PubMed: 29769321; DOI: 10.1074/jbc.RA117.001430

実験手法

X-RAY DIFFRACTION (1.898 Å)