6B9L
Crystal structure of EphA2 with peptide 135E2
Summary for 6B9L
Entry DOI | 10.2210/pdb6b9l/pdb |
Descriptor | Ephrin type-A receptor 2, peptide 135E2, (DUG)SAYPDSVPFR, HIS TAG CLEAVED OFF (3 entities in total) |
Functional Keywords | complex, ligand binding domain, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 9 |
Total formula weight | 94984.75 |
Authors | |
Primary citation | Gambini, L.,Salem, A.F.,Udompholkul, P.,Tan, X.F.,Baggio, C.,Shah, N.,Aronson, A.,Song, J.,Pellecchia, M. Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell. ACS Chem. Biol., 13:2633-2644, 2018 Cited by PubMed: 30110533DOI: 10.1021/acschembio.8b00556 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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