6B7O

Crystal structure of Legionella effector sdeD (lpg2509) H67A in complex with ADP-ribosylated Ubiquitin

6B7O の概要

• エントリーDOI: 10.2210/pdb6b7o/pdb
• 分子名称: SdeD (lpg2509) H67A, Polyubiquitin-C, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: legionella, ubiquitin, sded, adpr-ub, pr-ub, phosphodiesterase, cell invasion
• 由来する生物種: Legionella pneumophila; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 61084.93

構造登録者

Mao, Y.,Akturk, A.,Wasilko, J. (登録日: 2017-10-04, 公開日: 2018-04-18, 最終更新日: 2020-01-01)

• 主引用文献: Akturk, A.,Wasilko, D.J.,Wu, X.,Liu, Y.,Zhang, Y.,Qiu, J.,Luo, Z.Q.,Reiter, K.H.,Brzovic, P.S.,Klevit, R.E.,Mao, Y.; Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.; Nature, 557:729-733, 2018; PubMed: 29795346; DOI: 10.1038/s41586-018-0147-6

実験手法

X-RAY DIFFRACTION (1.85 Å)