6B7C

Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with N-((1,3-dimethyl-1H-pyrazol-5-yl)methyl)-5-methyl-1H-imidazo[4,5-b]pyridin-2-amine

6B7C の概要

• エントリーDOI: 10.2210/pdb6b7c/pdb
• 分子名称: Phosphopantetheine adenylyltransferase, N-[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]-5-methyl-3H-imidazo[4,5-b]pyridin-2-amine, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: coad, transferase
• 由来する生物種: Escherichia coli (strain K12)
• 細胞内の位置: Cytoplasm : P0A6I6
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 39606.99

構造登録者

Proudfoot, A.W.,Bussiere, D.,Lingel, A. (登録日: 2017-10-03, 公開日: 2017-12-27, 最終更新日: 2023-10-04)

• 主引用文献: Proudfoot, A.,Bussiere, D.E.,Lingel, A.; High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization.; J. Am. Chem. Soc., 139:17824-17833, 2017; PubMed: 29190085; DOI: 10.1021/jacs.7b07171

実験手法

X-RAY DIFFRACTION (1.564 Å)