6B4X

Schistosoma mansoni (Blood Fluke) Sulfotransferase, F39Y Mutant

Summary for 6B4X

• Entry DOI: 10.2210/pdb6b4x/pdb
• Descriptor: Sulfotransferase oxamniquine resistance protein, ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, ... (5 entities in total)
• Functional Keywords: sulfotransferase, parasite, drug resistance, transferase
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 30668.88

Authors

Taylor, A.B. (deposition date: 2017-09-27, release date: 2018-10-10, Last modification date: 2023-10-04)

• Primary citation: Rugel, A.R.,Guzman, M.A.,Taylor, A.B.,Chevalier, F.D.,Tarpley, R.S.,McHardy, S.F.,Cao, X.,Holloway, S.P.,Anderson, T.J.C.,Hart, P.J.,LoVerde, P.T.; Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?; Int.J.Parasitol., 2020; DOI: 10.1016/j.ijpddr.2020.04.001

Experimental method

X-RAY DIFFRACTION (1.46 Å)