6B46

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF1

Summary for 6B46

Entry DOI	10.2210/pdb6b46/pdb
Related	6B44 6B45 6B47 6B48
EMDB information	7048 7049 7050 7051 7052
Descriptor	CRISPR-associated protein Csy3, Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, ... (4 entities in total)
Functional Keywords	crispr-cas, immune system-hydrolase-rna complex, immune system/hydrolase/rna
Biological source	Pseudomonas aeruginosa (strain UCBPP-PA14) More
Total number of polymer chains	10
Total formula weight	285522.58
Authors	Guo, T.W.,Bartesaghi, A.,Yang, H.,Falconieri, V.,Rao, P.,Merk, A.,Fox, T.,Earl, L.,Patel, D.J.,Subramaniam, S. (deposition date: 2017-09-25, release date: 2017-10-18, Last modification date: 2024-03-13)
Primary citation	Guo, T.W.,Bartesaghi, A.,Yang, H.,Falconieri, V.,Rao, P.,Merk, A.,Eng, E.T.,Raczkowski, A.M.,Fox, T.,Earl, L.A.,Patel, D.J.,Subramaniam, S. Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell, 171:414-426.e12, 2017 Cited by PubMed: 28985564 DOI: 10.1016/j.cell.2017.09.006 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation