6B21

Crystal structure of AmtB from E. coli bound to TopFluor cardiolipin

6B21 の概要

• エントリーDOI: 10.2210/pdb6b21/pdb
• 分子名称: Ammonia channel, [(2R,5R,11R,14S,24E)-14-[(acetyloxy)methyl]-8-{[5-(3,5-dimethyl-1H-pyrrol-2-yl-kappaN)-5-(3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)pentanoyl]oxy}-5,11-dihydroxy-2-{[(9E)-octadec-9-enoyl]oxy}-5,11,16-trioxo-4,6,10,12,15-pentaoxa-5lambda~5~,11lambda~5~-diphosphatritriacont-24-en-1-yl (9E)-octadec-9-enoatato](difluoro)boron (3 entities in total)
• 機能のキーワード: ammonia channel, amtb, cardiolipin, transporter, membrane protein
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43855.21

構造登録者

Boone, C.D.,Laganowsky, A. (登録日: 2017-09-19, 公開日: 2018-03-07, 最終更新日: 2023-10-04)

• 主引用文献: Patrick, J.W.,Boone, C.D.,Liu, W.,Conover, G.M.,Liu, Y.,Cong, X.,Laganowsky, A.; Allostery revealed within lipid binding events to membrane proteins.; Proc. Natl. Acad. Sci. U.S.A., 115:2976-2981, 2018; PubMed: 29507234; DOI: 10.1073/pnas.1719813115

実験手法

X-RAY DIFFRACTION (2.45 Å)