6AYO

Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with 5'-deoxy-5'-Propyl-DADMe-Immucillin-A

6AYO の概要

• エントリーDOI: 10.2210/pdb6ayo/pdb
• 分子名称: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-propylpyrrolidin-3-ol, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: mtan enzyme, foodborne diseases, hydrolase, transferase
• 由来する生物種: Campylobacter jejuni
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53633.06

構造登録者

Harijan, R.K.,Ducati, R.G.,Bonanno, J.B.,Almo, S.C.,Schramm, V.L. (登録日: 2017-09-08, 公開日: 2018-09-12, 最終更新日: 2023-10-04)

• 主引用文献: Ducati, R.G.,Harijan, R.K.,Cameron, S.A.,Tyler, P.C.,Evans, G.B.,Schramm, V.L.; Transition-State Analogues of Campylobacter jejuni 5'-Methylthioadenosine Nucleosidase.; ACS Chem. Biol., 13:3173-3183, 2018; PubMed: 30339406; DOI: 10.1021/acschembio.8b00781

実験手法

X-RAY DIFFRACTION (1.67 Å)