6AX5

RPT1 region of INI1/SNF5/SMARCB1_HUMAN - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1.

Summary for 6AX5

• Entry DOI: 10.2210/pdb6ax5/pdb
• NMR Information: BMRB: 27243
• Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (1 entity in total)
• Functional Keywords: rpt1, ini1, actin-dependent regulator, nuclear protein
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus: Q12824
• Total number of polymer chains: 1
• Total formula weight: 9572.92

Authors

Girvin, M.E.,Cahill, S.M.,Harris, R.,Cowburn, D.,Spira, M.,Wu, X.,Prakash, R.,Bernowitz, M.,Almo, S.C.,Kalpana, G.V. (deposition date: 2017-09-06, release date: 2017-10-18, Last modification date: 2023-06-14)

• Primary citation: Dixit, U.,Bhutoria, S.,Wu, X.,Qiu, L.,Spira, M.,Mathew, S.,Harris, R.,Adams, L.J.,Cahill, S.,Pathak, R.,Rajesh Kumar, P.,Nguyen, M.,Acharya, S.A.,Brenowitz, M.,Almo, S.C.,Zou, X.,Steven, A.C.,Cowburn, D.,Girvin, M.,Kalpana, G.V.; INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.; Nat Commun, 12:2743-2743, 2021; PubMed: 33980829; DOI: 10.1038/s41467-021-22733-9

Experimental method

SOLUTION NMR