6AWJ
Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-MeO-N5Pan with pantothenate present in reaction
Summary for 6AWJ
Entry DOI | 10.2210/pdb6awj/pdb |
Descriptor | Type II pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, (2R)-2-hydroxy-N-{3-[(5-methoxypentyl)amino]-3-oxopropyl}-3,3-dimethylbutanamide, ... (4 entities in total) |
Functional Keywords | staphylococcus aureus, sapank, adp, pantothenate analog, transferase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 118909.52 |
Authors | Chen, Y.,Antoshchenko, T.,Strauss, E.,Barnard, L.,Huang, Y.H. (deposition date: 2017-09-05, release date: 2018-09-12, Last modification date: 2024-03-13) |
Primary citation | Chen, Y.,Antoshchenko, T.,Strauss, E.,Barnard, L.,Huang, Y.H. Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase. To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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