6ATH
Cdk2/cyclin A/p27-KID-deltaC
Summary for 6ATH
Entry DOI | 10.2210/pdb6ath/pdb |
Descriptor | Cyclin-dependent kinase 2, Cyclin-A2, Cyclin-dependent kinase inhibitor 1B, ... (5 entities in total) |
Functional Keywords | inhibitor, complex, idp, cdk, cyclin, kinase, phosphortlation, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 72545.48 |
Authors | White, S.W.,Yun, M. (deposition date: 2017-08-29, release date: 2018-09-12, Last modification date: 2023-10-04) |
Primary citation | Tsytlonok, M.,Sanabria, H.,Wang, Y.,Felekyan, S.,Hemmen, K.,Phillips, A.H.,Yun, M.K.,Waddell, M.B.,Park, C.G.,Vaithiyalingam, S.,Iconaru, L.,White, S.W.,Tompa, P.,Seidel, C.A.M.,Kriwacki, R. Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation. Nat Commun, 10:1676-1676, 2019 Cited by PubMed: 30976006DOI: 10.1038/s41467-019-09446-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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