6AQN

Crystal structure of PPK2 in complex with phosphonic acid inhibitor

6AQN の概要

• エントリーDOI: 10.2210/pdb6aqn/pdb
• 関連するPDBエントリー: 6AN9 6ANG
• 分子名称: Polyphosphate:AMP phosphotransferase, [(R)-hydroxy(4-methylphenyl)methyl]phosphonic acid, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: ppk2, kinase, inhibitor, (hydroxy(p-toluyl)methyl)phosphonic acid, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35984.07

構造登録者

Nocek, B.,Berlicki, l.,Joachimiak, A.,Yakunin, S. (登録日: 2017-08-20, 公開日: 2019-01-16, 最終更新日: 2023-11-15)

• 主引用文献: Nocek, B.,Khusnutdinova, A.N.,Ruszkowski, M.,Flick, R.,Burda, M.,Batyrova, K.,Brown, G.,Mucha, A.,Joachimiak, A.,Berlicki, L.,Yakunin, A.F.; Structural Insights into Substrate Selectivity and Activity of Bacterial Polyphosphate Kinases; Acs Catalysis, 8:10746-10760, 2018; DOI: 10.1021/acscatal.8b03151

実験手法

X-RAY DIFFRACTION (2.199 Å)