6AO4
Crystal structure of the human gasdermin D C-terminal domain
Summary for 6AO4
Entry DOI | 10.2210/pdb6ao4/pdb |
Descriptor | Gasdermin-D (1 entity in total) |
Functional Keywords | inflammasome, pyroptosis, gasdermin d, autoinhibition, salmonella infection, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 22354.44 |
Authors | Liu, Z.,Wang, C.,Yang, J.,Xiao, T.S. (deposition date: 2017-08-15, release date: 2018-04-11, Last modification date: 2023-10-04) |
Primary citation | Liu, Z.,Wang, C.,Rathkey, J.K.,Yang, J.,Dubyak, G.R.,Abbott, D.W.,Xiao, T.S. Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition. Structure, 26:778-784.e3, 2018 Cited by PubMed: 29576317DOI: 10.1016/j.str.2018.03.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.901 Å) |
Structure validation
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