6AO3

Crystal structure of the murine gasdermin D C-terminal domain

Summary for 6AO3

Entry DOI	10.2210/pdb6ao3/pdb
Descriptor	Gasdermin-D (2 entities in total)
Functional Keywords	inflammasome, pyroptosis, gasdermin d, autoinhibition, salmonella infection, immune system
Biological source	Mus musculus (Mouse)
Total number of polymer chains	4
Total formula weight	92052.70
Authors	Liu, Z.,Wang, C.,Yang, J.,Xiao, T.S. (deposition date: 2017-08-15, release date: 2018-04-11, Last modification date: 2024-03-13)
Primary citation	Liu, Z.,Wang, C.,Rathkey, J.K.,Yang, J.,Dubyak, G.R.,Abbott, D.W.,Xiao, T.S. Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition. Structure, 26:778-784.e3, 2018 Cited by PubMed: 29576317 DOI: 10.1016/j.str.2018.03.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation