6AHS

Mouse Kallikrein 7 in complex with imidazolinylindole derivative

6AHS の概要

• エントリーDOI: 10.2210/pdb6ahs/pdb
• 分子名称: Kallikrein-7, 1-[(2-chlorophenyl)sulfonyl]-5-methyl-3-[(4R)-2-methyl-4,5-dihydro-1H-imidazol-4-yl]-1H-indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• 機能のキーワード: protease, hydrolase
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25218.27

構造登録者

Sugawara, H. (登録日: 2018-08-20, 公開日: 2019-01-02, 最終更新日: 2023-11-22)

• 主引用文献: Murafuji, H.,Muto, T.,Goto, M.,Imajo, S.,Sugawara, H.,Oyama, Y.,Minamitsuji, Y.,Miyazaki, S.,Murai, K.,Fujioka, H.; Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors.; Bioorg. Med. Chem. Lett., 29:334-338, 2019; PubMed: 30522951; DOI: 10.1016/j.bmcl.2018.11.011

実験手法

X-RAY DIFFRACTION (1.75 Å)