CryoEM Reconstruction of Hsp104 N728A Hexamer

Summary for 6AHF

EMDB information9625
DescriptorHeat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (2 entities in total)
Functional Keywordschaperone, hsp, holdase
Biological sourceSaccharomyces cerevisiae S288c (Baker's yeast)
Total number of polymer chains6
Total molecular weight615925.11
Zhang, X.,Zhang, L.,Zhang, S. (deposition date: 2018-08-17, release date: 2019-02-13, Last modification date: 2019-02-20)
Primary citation
Zhang, X.,Zhang, S.,Zhang, L.,Lu, J.,Zhao, C.,Luo, F.,Li, D.,Li, X.,Liu, C.
Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity.
J. Biol. Chem., 2019
PubMed: 30718279 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA118.005980
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers154 4.7% 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 6ahf
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Molmil generated image of 6ahf
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Molmil generated image of 6ahf
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