6AG3

Crystal structure of uPA in complex with 3,5-bis(azanyl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide

Summary for 6AG3

• Entry DOI: 10.2210/pdb6ag3/pdb
• Descriptor: Urokinase-type plasminogen activator, 3,5-bis(azanyl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide (3 entities in total)
• Functional Keywords: urokinase, amiloride, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 28775.68

Authors

Buckley, B.,Jiang, L.G.,Majed, H.,Huang, M.D.,Kelso, M.,Ranson, M. (deposition date: 2018-08-09, release date: 2019-09-18, Last modification date: 2023-11-22)

• Primary citation: Buckley, B.,Jiang, L.G.,Huang, M.D.,Kelso, M.,Ranson, M.; uPA-HMA; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.48 Å)