6AEL

Crystal structure of ENPP1 in complex with 3'3'-cGAMP

6AEL の概要

• エントリーDOI: 10.2210/pdb6ael/pdb
• 分子名称: Ectonucleotide pyrophosphatase/phosphodiesterase 1, isoform CRA_d, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: enzyme, phoshodiesterase, cgamp, cgas-sting, cyclic gmp-amp, immunosuppressant
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 87620.89

構造登録者

Kato, K.,Nishimasu, H.,Hirano, S.,Hirano, H.,Ishitani, R.,Nureki, O. (登録日: 2018-08-05, 公開日: 2019-03-06, 最終更新日: 2023-11-22)

• 主引用文献: Kato, K.,Nishimasu, H.,Oikawa, D.,Hirano, S.,Hirano, H.,Kasuya, G.,Ishitani, R.,Tokunaga, F.,Nureki, O.; Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.; Nat Commun, 9:4424-4424, 2018; PubMed: 30356045; DOI: 10.1038/s41467-018-06922-7

実験手法

X-RAY DIFFRACTION (1.9 Å)