6A8G
The crystal structure of muPAin-1-IG in complex with muPA-SPD at pH8.5
Summary for 6A8G
Entry DOI | 10.2210/pdb6a8g/pdb |
Descriptor | muPAin-1-IG, Urokinase-type plasminogen activator chain B, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | peptides inhibitor, mupa, serine protease, hydrolase, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 57897.91 |
Authors | Wang, D.,Yang, Y.S.,Jiang, L.G.,Huang, M.D.,Li, J.Y.,Andreasen, P.A.,Xu, P.,Chen, Z. (deposition date: 2018-07-08, release date: 2019-02-20, Last modification date: 2023-11-22) |
Primary citation | Wang, D.,Yang, Y.,Jiang, L.,Wang, Y.,Li, J.,Andreasen, P.A.,Chen, Z.,Huang, M.,Xu, P. Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. J.Med.Chem., 62:2172-2183, 2019 Cited by PubMed: 30707839DOI: 10.1021/acs.jmedchem.8b01908 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.53 Å) |
Structure validation
Download full validation report