6A0P

Crystal structure of Usutu virus envelope protein in the pre-fusion state

6A0P の概要

• エントリーDOI: 10.2210/pdb6a0p/pdb
• 分子名称: Envelope protein (2 entities in total)
• 機能のキーワード: usutu virus, envelope, pre-fusion state, domain-angle difference, viral protein
• 由来する生物種: Usutu virus (USUV)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44756.45

構造登録者

Lu, G.,Chen, Z.,Ye, F.,Lin, S.,Yang, F.,Cheng, Y. (登録日: 2018-06-06, 公開日: 2018-12-26, 最終更新日: 2024-11-20)

主引用文献

Chen, Z.,Ye, F.,Lin, S.,Yang, F.,Cheng, Y.,Cao, Y.,Chen, Z.,Lu, G.
Crystal structure of Usutu virus envelope protein in the pre-fusion state
Virol. J., 15:183-183, 2018

PubMed Abstract: Usutu virus (USUV) is a mosquito-born flavivirus that can infect multiple avian and mammalian species. The viral surface envelope (E) protein functions to initiate the viral infection by recognizing cellular receptors and mediating the subsequent membrane fusion, and is therefore a key virulence factor involved in the pathogenesis of USUV. The structural features of USUV-E, however, remains un-investigated thus far.

PubMed: 30477514
DOI: 10.1186/s12985-018-1092-6

実験手法

X-RAY DIFFRACTION (2 Å)