6A05

Structure of pSTING complex

Summary for 6A05

Entry DOI	10.2210/pdb6a05/pdb
Descriptor	Stimulator of interferon genes protein, SULFATE ION, 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, ... (4 entities in total)
Functional Keywords	psting, signaling protein
Biological source	Sus scrofa (Pig)
Total number of polymer chains	2
Total formula weight	46630.12
Authors	Yuan, Z.L.,Shang, G.J.,Cong, X.Y.,Gu, L.C. (deposition date: 2018-06-05, release date: 2019-06-19, Last modification date: 2024-03-27)
Primary citation	Cong, X.,Yuan, Z.,Du, Y.,Wu, B.,Lu, D.,Wu, X.,Zhang, Y.,Li, F.,Wei, B.,Li, J.,Wu, J.,Xu, S.,Wang, J.,Qi, J.,Shang, G.,Gu, L. Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins. J.Biol.Chem., 294:11420-11432, 2019 Cited by PubMed: 31167783 DOI: 10.1074/jbc.RA119.007367 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation