Structure of pSTING complex

Summary for 6A03

DescriptorStimulator of interferon genes protein, SULFATE ION, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ... (4 entities in total)
Functional Keywordspsting, signaling protein
Biological sourceSus scrofa (Pig)
Total number of polymer chains2
Total molecular weight46422
Yuan, Z.L.,Shang, G.J.,Cong, X.Y.,Gu, L.C. (deposition date: 2018-06-05, release date: 2019-06-19, Last modification date: 2019-08-07)
Primary citation
Cong, X.,Yuan, Z.,Du, Y.,Wu, B.,Lu, D.,Wu, X.,Zhang, Y.,Li, F.,Wei, B.,Li, J.,Wu, J.,Xu, S.,Wang, J.,Qi, J.,Shang, G.,Gu, L.
Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins.
J.Biol.Chem., 294:11420-11432, 2019
PubMed: 31167783 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA119.007367
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25660 2.3% 3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution