6ZP3
Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 2-Methylindole-3-acetic acid
Summary for 6ZP3
Entry DOI | 10.2210/pdb6zp3/pdb |
Descriptor | Thioredoxin glutathione reductase, TRIETHYLENE GLYCOL, FLAVIN-ADENINE DINUCLEOTIDE, ... (11 entities in total) |
Functional Keywords | fragment binding, redox enzyme, inhibitor, protein binding |
Biological source | Schistosoma mansoni |
Total number of polymer chains | 1 |
Total formula weight | 66844.88 |
Authors | Fata, F.,Silvestri, I.,Williams, D.L.,Angelucci, F. (deposition date: 2020-07-08, release date: 2021-05-19, Last modification date: 2024-01-31) |
Primary citation | Fata, F.,Silvestri, I.,Ardini, M.,Ippoliti, R.,Di Leandro, L.,Demitri, N.,Polentarutti, M.,Di Matteo, A.,Lyu, H.,Thatcher, G.R.J.,Petukhov, P.A.,Williams, D.L.,Angelucci, F. Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments. Acs Infect Dis., 7:1932-1944, 2021 Cited by PubMed: 33950676DOI: 10.1021/acsinfecdis.0c00909 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report