6Z84
CK2 alpha bound to chemical probe SGC-CK2-1 derivative
This is a non-PDB format compatible entry.
Summary for 6Z84
Entry DOI | 10.2210/pdb6z84/pdb |
Descriptor | Casein kinase II subunit alpha, SULFATE ION, ~{N}-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]ethanamide, ... (4 entities in total) |
Functional Keywords | kinase, inhibitor, chemical probe, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 82551.50 |
Authors | Kraemer, A.,Wells, C.,Drewry, D.H.,Pickett, J.E.,Axtman, A.D.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-06-02, release date: 2020-07-29, Last modification date: 2024-01-24) |
Primary citation | Wells, C.I.,Drewry, D.H.,Pickett, J.E.,Tjaden, A.,Kramer, A.,Muller, S.,Gyenis, L.,Menyhart, D.,Litchfield, D.W.,Knapp, S.,Axtman, A.D. Development of a potent and selective chemical probe for the pleiotropic kinase CK2. Cell Chem Biol, 28:546-558.e10, 2021 Cited by PubMed: 33484635DOI: 10.1016/j.chembiol.2020.12.013 PDB entries with the same primary citation |
Experimental method |
Structure validation
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