6Z43

Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex

Summary for 6Z43

• Entry DOI: 10.2210/pdb6z43/pdb
• EMDB information: 11068
• Descriptor: Spike glycoprotein, Nanobody, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: spike, nanobody, vhh, sars-cov-2, covid-19, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 491475.91

Authors

Ruza, R.R.,Duyvesteyn, H.M.E.,Shah, P.,Carrique, L.,Ren, J.,Malinauskas, T.,Zhou, D.,Stuart, D.I.,Naismith, J.H. (deposition date: 2020-05-22, release date: 2020-06-03, Last modification date: 2024-10-16)

• Primary citation: Huo, J.,Le Bas, A.,Ruza, R.R.,Duyvesteyn, H.M.E.,Mikolajek, H.,Malinauskas, T.,Tan, T.,Rijal, P.,Dumoux, M.,Ward, P.N.,Ren, J.,Zhou, D.,Harrison, P.J.,Radecke, J.,Zhao, Y.,Jaramillo, J.G.,Knight, M.,Carrique, L.,Shah, P.,James, W.,Townsend, A.,Stuart, D.I.,Owens, R.J.,Naismith, J.H.; Structural basis for a potent neutralising single-domain antibody that blocks SARS-CoV-2 binding to its receptor ACE2; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)