6Z2E

Crystal structure of SARS-CoV-2 Mpro in complex with the activity-based probe, biotin-PEG(4)-Abu-Tle-Leu-Gln-vinylsulfone

This is a non-PDB format compatible entry.

Summary for 6Z2E

• Entry DOI: 10.2210/pdb6z2e/pdb
• Descriptor: 3C-like proteinase, (4~{S})-4-[[(2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-[3-[2-[2-[2-[2-[5-[(3~{a}~{S},4~{R},6~{a}~{R})-2-oxidanylidene-3,3~{a},4,6~{a}-tetrahydro-1~{H}-thieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]butanoyl]amino]-3,3-dimethyl-butanoyl]amino]-4-methyl-pentanoyl]amino]-6-methylsulfonyl-hexanamide, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: sars-cov-2, main protease, activity-based probe, inhibitor, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• Total number of polymer chains: 1
• Total formula weight: 34912.72

Authors

Zhang, L.,Hilgenfeld, R. (deposition date: 2020-05-15, release date: 2020-06-17, Last modification date: 2024-01-24)

• Primary citation: Zhang, L.,Hilgenfeld, R.; Crystal structure of SARS-CoV-2 Mpro in complex with the activity-based probe, biotin-PEG(4)-Abu-Tle-Leu-Gln-vinylsulfone; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)