6YQU
CRYSTAL STRUCTURE OF HUMAN CA II IN COMPLEX WITH 2-MERCAPTOBENZOXAZOLE
Summary for 6YQU
Entry DOI | 10.2210/pdb6yqu/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, 3~{H}-1,3-benzoxazole-2-thione, ... (6 entities in total) |
Functional Keywords | mercaptobenzoxazole, carbonic anhydrase, inhibitor complex, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29754.02 |
Authors | Alterio, V.,De Simone, G.,Esposito, D. (deposition date: 2020-04-18, release date: 2020-07-01, Last modification date: 2024-01-24) |
Primary citation | Bozdag, M.,Supuran, C.T.,Esposito, D.,Angeli, A.,Carta, F.,Monti, S.M.,De Simone, G.,Alterio, V. 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site. Chem.Commun.(Camb.), 56:8297-8300, 2020 Cited by PubMed: 32573627DOI: 10.1039/d0cc02857f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.478 Å) |
Structure validation
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