6XZS
Crystal structure of human carbonic anhydrase I in complex with 4-(3-(2-((4-fluorobenzyl)amino)ethyl)ureido) benzenesulfonamide
Summary for 6XZS
Entry DOI | 10.2210/pdb6xzs/pdb |
Related | 6xze 6xzo |
Descriptor | Carbonic anhydrase 1, ZINC ION, 1-[2-[(4-fluorophenyl)methylamino]ethyl]-3-(4-sulfamoylphenyl)urea, ... (4 entities in total) |
Functional Keywords | inhibitor, carbon dioxide, carbonic anhydrase, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 58676.01 |
Authors | Zanotti, G.,Majid, A.,Bozdag, M.,Angeli, A.,Carta, F.,Berto, F.,Supuran, C.T. (deposition date: 2020-02-05, release date: 2020-09-23, Last modification date: 2024-01-24) |
Primary citation | Ali, M.,Bozdag, M.,Farooq, U.,Angeli, A.,Carta, F.,Berto, P.,Zanotti, G.,Supuran, C.T. Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases. Int J Mol Sci, 21:-, 2020 Cited by PubMed: 32272689DOI: 10.3390/ijms21072560 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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