6XD1
Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-640
Summary for 6XD1
Entry DOI | 10.2210/pdb6xd1/pdb |
Descriptor | RNA-dependent RNA polymerase, ZINC ION, (2R)-4-(butyl{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}carbamoyl)-1-(2,2-diphenylpropanoyl)piperazine-2-carboxylic acid, ... (4 entities in total) |
Functional Keywords | dengue rdrp, transferase |
Biological source | Dengue virus 3 |
Total number of polymer chains | 1 |
Total formula weight | 74427.47 |
Authors | Arora, R.,Benson, T.E.,Liew, C.W.,Lescar, J. (deposition date: 2020-06-09, release date: 2020-09-23, Last modification date: 2024-05-22) |
Primary citation | Arora, R.,Liew, C.W.,Soh, T.S.,Otoo, D.A.,Seh, C.C.,Yue, K.,Nilar, S.,Wang, G.,Yokokawa, F.,Noble, C.G.,Chen, Y.L.,Shi, P.Y.,Lescar, J.,Smith, T.M.,Benson, T.E.,Lim, S.P. Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies. J.Virol., 94:-, 2020 Cited by PubMed: 32907977DOI: 10.1128/JVI.01130-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.954 Å) |
Structure validation
Download full validation report