6WIA
CRYSTAL STRUCTURE OF HUMAN PROTECTIVE PROTEIN/CATHEPSIN A, DFP-INHIBITED (AGED)
Summary for 6WIA
Entry DOI | 10.2210/pdb6wia/pdb |
Descriptor | Lysosomal protective protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... (6 entities in total) |
Functional Keywords | lysosomal, cathepsin a, cata, ctsa, organophosphate, renin-angiotensin system (ras), hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 54317.49 |
Authors | Compton, J.R.,Legler, P.M. (deposition date: 2020-04-09, release date: 2020-04-29, Last modification date: 2023-10-18) |
Primary citation | Bouknight, K.D.,Jurkouich, K.M.,Compton, J.R.,Khavrutskii, I.V.,Guelta, M.A.,Harvey, S.P.,Legler, P.M. Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A. Biochem. Pharmacol., 177:113980-113980, 2020 Cited by PubMed: 32305437DOI: 10.1016/j.bcp.2020.113980 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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