6W4Z

Galectin-8N terminal domain in complex with Methyl 3-O-[3-O-benzyloxy]-malonyl-beta-D-galactopyranoside

Summary for 6W4Z

Entry DOI	10.2210/pdb6w4z/pdb
Descriptor	Galectin-8, methyl 3-O-[3-(benzyloxy)-3-oxopropanoyl]-beta-D-galactopyranoside, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	galectin-8n, sugar binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	35678.37
Authors	Patel, B.,Kishor, C.,Blanchard, H. (deposition date: 2020-03-12, release date: 2020-09-02, Last modification date: 2023-10-18)
Primary citation	Patel, B.,Kishor, C.,Houston, T.A.,Shatz-Azoulay, H.,Zick, Y.,Vinik, Y.,Blanchard, H. Rational Design and Synthesis of Methyl-beta-d-galactomalonyl Phenyl Esters as Potent Galectin-8 N Antagonists. J.Med.Chem., 63:11573-11584, 2020 Cited by PubMed: 32809817 DOI: 10.1021/acs.jmedchem.0c00602 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation