6UX6

Cruzain covalently bound by a vinylsulfone compound

Summary for 6UX6

• Entry DOI: 10.2210/pdb6ux6/pdb
• Descriptor: Cruzipain, Nalpha-[(benzyloxy)carbonyl]-N-[(2S)-1-phenyl-4-(phenylsulfonyl)butan-2-yl]-L-phenylalaninamide, GLYCEROL, ... (4 entities in total)
• Functional Keywords: cruzain, vinylsulfone, covalent, inhibitor, hydrolase
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 1
• Total formula weight: 23377.93

Authors

Zhai, X.,Tang, S.,Chenna, B.C.,Meek, T.D.,Sacchettini, J.C. (deposition date: 2019-11-06, release date: 2020-11-25, Last modification date: 2023-10-11)

• Primary citation: Zhai, X.,Tang, S.,Chenna, B.C.,Meek, T.D.,Sacchettini, J.C.; Cruzain covalently bound by a vinylsulfone compound; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.94 Å)