6UDA
Cryo-EM structure of CH235UCA bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664
Summary for 6UDA
Entry DOI | 10.2210/pdb6uda/pdb |
EMDB information | 20735 |
Descriptor | CH505.N279K.G458Y.SOSIP.664 gp120, CH235 UCA heavy chain Fab, CH505.N279K.G458Y.SOSIP.664 gp41, ... (6 entities in total) |
Functional Keywords | ch235 lineage, ch505 virus, vaccine design, cryo-em, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 12 |
Total formula weight | 378539.12 |
Authors | Henderson, R.,Acharya, P. (deposition date: 2019-09-19, release date: 2019-10-02, Last modification date: 2020-07-29) |
Primary citation | LaBranche, C.C.,Henderson, R.,Hsu, A.,Behrens, S.,Chen, X.,Zhou, T.,Wiehe, K.,Saunders, K.O.,Alam, S.M.,Bonsignori, M.,Borgnia, M.J.,Sattentau, Q.J.,Eaton, A.,Greene, K.,Gao, H.,Liao, H.X.,Williams, W.B.,Peacock, J.,Tang, H.,Perez, L.G.,Edwards, R.J.,Kepler, T.B.,Korber, B.T.,Kwong, P.D.,Mascola, J.R.,Acharya, P.,Haynes, B.F.,Montefiori, D.C. Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancester of CH235 lineage CD4bs broadly neutralizing antibodies. Plos Pathog., 15:e1008026-e1008026, 2019 Cited by PubMed: 31527908DOI: 10.1371/journal.ppat.1008026 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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