6U7U

NMR solution structure of triazole bridged matriptase inhibitor

Summary for 6U7U

• Entry DOI: 10.2210/pdb6u7u/pdb
• NMR Information: BMRB: 30669
• Descriptor: GLY-ARG-ALA-THR-LYS-SER-ILE-PRO-PRO-ARG-ALA-PHE-PRO-ASP, 1-methyl-1H-1,2,3-triazole (2 entities in total)
• Functional Keywords: triazole, disulfide mimetic, inhibitor, biosynthetic protein
• Biological source: Helianthus annuus
• Total number of polymer chains: 1
• Total formula weight: 1598.83

Authors

White, A.M.,Harvey, P.J.,Durek, T.,Craik, D.J. (deposition date: 2019-09-03, release date: 2020-04-22, Last modification date: 2020-07-15)

• Primary citation: White, A.M.,de Veer, S.J.,Wu, G.,Harvey, P.J.,Yap, K.,King, G.J.,Swedberg, J.E.,Wang, C.K.,Law, R.H.P.,Durek, T.,Craik, D.J.; Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides.; Angew.Chem.Int.Ed.Engl., 59:11273-11277, 2020; PubMed: 32270580; DOI: 10.1002/anie.202003435

Experimental method

SOLUTION NMR