6U2S
Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
Summary for 6U2S
| Entry DOI | 10.2210/pdb6u2s/pdb |
| Descriptor | Bi-component leukocidin LukED subunit D, fos-choline-14 (3 entities in total) |
| Functional Keywords | alpha-toxin, pvl, leukocidins, mrsa, toxin |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 1 |
| Total formula weight | 34961.57 |
| Authors | Liu, J.,Kozhaya, L.,Torres, V.J.,Unutmaz, D.,Lu, M. (deposition date: 2019-08-20, release date: 2020-03-25, Last modification date: 2023-10-11) |
| Primary citation | Liu, J.,Kozhaya, L.,Torres, V.J.,Unutmaz, D.,Lu, M. Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295:5944-5959, 2020 Cited by PubMed: 32179646DOI: 10.1074/jbc.RA120.012697 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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