6TT4
Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with omapatrilat.
Summary for 6TT4
Entry DOI | 10.2210/pdb6tt4/pdb |
Descriptor | Angiotensin-converting enzyme, CHLORIDE ION, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, ... (17 entities in total) |
Functional Keywords | angiotensin-1 converting enzyme, ace inhibitor, omapatrilat, metalloprotease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 150983.72 |
Authors | Cozier, G.E.,Acharya, K.R. (deposition date: 2019-12-23, release date: 2020-04-01, Last modification date: 2024-01-24) |
Primary citation | Cozier, G.E.,Lubbe, L.,Sturrock, E.D.,Acharya, K.R. ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477:1241-1259, 2020 Cited by PubMed: 32195541DOI: 10.1042/BCJ20200060 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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