6TMA
VIM-2_1dj- Triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-beta-lactamases
Summary for 6TMA
Entry DOI | 10.2210/pdb6tma/pdb |
Descriptor | Beta-lactamase class B VIM-2, ZINC ION, HYDROXIDE ION, ... (7 entities in total) |
Functional Keywords | metallo-beta-lactamase inhibitor, nh-triazole, inhibition properties, crystal structure., antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 58148.42 |
Authors | Leiros, H.-K.S. (deposition date: 2019-12-03, release date: 2020-09-02, Last modification date: 2024-01-24) |
Primary citation | Muhammad, Z.,Skagseth, S.,Boomgaren, M.,Akhter, S.,Frohlich, C.,Ismael, A.,Christopeit, T.,Bayer, A.,Leiros, H.S. Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-beta-lactamases. Bioorg.Med.Chem., 28:115598-115598, 2020 Cited by PubMed: 32631568DOI: 10.1016/j.bmc.2020.115598 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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