6TCK

Crystal structure of the ATP binding domain of S. aureus GyrB complexed with ULD-2

Summary for 6TCK

• Entry DOI: 10.2210/pdb6tck/pdb
• Descriptor: DNA gyrase subunit B, 2-[[3,4-bis(chloranyl)-5-methyl-1~{H}-pyrrol-2-yl]carbonylamino]-4-phenylmethoxy-1,3-benzothiazole-6-carboxylic acid, GLYCEROL, ... (9 entities in total)
• Functional Keywords: dna gyrase, gyrb, isomerase
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 2
• Total formula weight: 49757.04

Authors

Welin, M.,Kimbung, R.,Focht, D. (deposition date: 2019-11-06, release date: 2020-09-23, Last modification date: 2024-01-24)

• Primary citation: Nyerges, A.,Tomasic, T.,Durcik, M.,Revesz, T.,Szili, P.,Draskovits, G.,Bogar, F.,Skok, Z.,Zidar, N.,Ilas, J.,Zega, A.,Kikelj, D.,Daruka, L.,Kintses, B.,Vasarhelyi, B.,Foldesi, I.,Kata, D.,Welin, M.,Kimbung, R.,Focht, D.,Masic, L.P.,Pal, C.; Rational design of balanced dual-targeting antibiotics with limited resistance.; Plos Biol., 18:e3000819-e3000819, 2020; PubMed: 33017402; DOI: 10.1371/journal.pbio.3000819

Experimental method