6TBK
Structure of a beta galactosidase with inhibitor
Summary for 6TBK
Entry DOI | 10.2210/pdb6tbk/pdb |
Descriptor | Beta-galactosidase, putative, bgl35A, SODIUM ION, 5-(dimethylamino)-~{N}-[6-[(2~{R},3~{R},4~{S},5~{R})-3-(hydroxymethyl)-4,5-bis(oxidanyl)piperidin-2-yl]hexyl]naphthalene-1-sulfonamide, ... (4 entities in total) |
Functional Keywords | beta galactosidase, inhibitor, hydrolase |
Biological source | Cellvibrio japonicus Ueda107 |
Total number of polymer chains | 8 |
Total formula weight | 501588.93 |
Authors | Offen, W.,Davies, G. (deposition date: 2019-11-01, release date: 2020-08-19, Last modification date: 2024-01-24) |
Primary citation | Weber, P.,Thonhofer, M.,Averill, S.,Davies, G.J.,Santana, A.G.,Muller, P.,Nasseri, S.A.,Offen, W.A.,Pabst, B.M.,Paschke, E.,Schalli, M.,Torvisco, A.,Tschernutter, M.,Tysoe, C.,Windischhofer, W.,Withers, S.G.,Wolfsgruber, A.,Wrodnigg, T.M.,Stutz, A.E. Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine. Molecules, 25:-, 2020 Cited by PubMed: 32899288DOI: 10.3390/molecules25174025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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