6T8M
Prolyl Hydroxylase (PHD) involved in hypoxia sensing by Dictyostelium discoideum
Summary for 6T8M
Entry DOI | 10.2210/pdb6t8m/pdb |
Descriptor | Prolyl 4-hydroxylase subunit alpha, NICKEL (II) ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | prolyl hydroxylase, oxygen sensing, 2-oxoglutarate and iron dependent oxygenase, oxidoreductase |
Biological source | Dictyostelium discoideum |
Total number of polymer chains | 3 |
Total formula weight | 81967.03 |
Authors | Chowdhury, R.,McDonough, M.A.,Liu, T.,Clifton, I.J.,Schofield, C.J. (deposition date: 2019-10-24, release date: 2020-09-23, Last modification date: 2024-01-24) |
Primary citation | Liu, T.,Abboud, M.I.,Chowdhury, R.,Tumber, A.,Hardy, A.P.,Lippl, K.,Lohans, C.T.,Pires, E.,Wickens, J.,McDonough, M.A.,West, C.M.,Schofield, C.J. Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii . J.Biol.Chem., 295:16545-16561, 2020 Cited by PubMed: 32934009DOI: 10.1074/jbc.RA120.013998 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
Download full validation report